Antimicrobial Susceptibility Discs Antibiotic Discs for all the Antibiotics are prepared as per guidelines of the Clinical and Laboratory Standards Institute (CLSI) formerly NCCL. Quality control of Antibiotic Discs are maintained using ATCC strains of different organisms as per guideline of CLSI. Discs for penicillins, all cephalosporins of 1st, 2nd, 3rd & 4th generations, macrolides, aminoglycosides, carbapenems and antifungal agents, etc. are included in the list.